What was diethyl ether called in the 1840s




















Wells had indeed made an amazing discovery, but he faced both skeptics and detractors. His demonstration of tooth-pulling under nitrous oxide at Massachusetts General Hospital in January failed to convince doctors and medical students when his patient moved about and groaned during the procedure, even though the man insisted afterward that he had felt no pain. And a former business partner, a fellow dentist and doctor named William T. Morton, soon tried to take credit for proposing an inhaled anesthetic.

Morton, a relentless self-promoter and schemer, stole money and ideas from others, then tried to take sole credit for shared innovations. Despite his shady character he played a leading role in the first public demonstration of ether as a general anesthetic for surgery. When the man awoke, he reported feeling as though his neck had been scratched. Its use for surgery, dentistry, and childbirth spread rapidly, and Morton failed to make a fortune from the discovery.

Ether also seeped into popular culture, fascinating people with its ability to vanquish pain. So if aches and pains should torture you, On Ether spend your money; You may be drawn and quartered too, And only think it funny.

As more and more people experienced surgery and dentistry in an etheric haze, such cartoons may have helped to alleviate anxiety about this new, mind-altering substance and its effects. The next major breakthrough in anesthesia came in In an elegant dining room in Edinburgh, Scottish surgeon and obstetrician Sir James Young Simpson ran a series of experiments to find inhaled painkillers that would be less smelly and flammable than ether and have fewer side effects.

The three Edinburgh doctors poured out the chloroform, raised their glasses to their noses, and breathed in deeply. A sweet smell filled the air, and the younger physicians became lively and talkative. The next he knew, he was looking up at the ceiling, with noise and confusion all around. Duncan had collapsed under a chair, snoring loudly, and Keith lay on his back under the table, kicking it violently despite his unconsciousness.

After gradually waking up and struggling back into their seats, the doctors were eager to experiment again—though more cautiously this time. Other family members watched these remarkable events.

The group continued to sniff the chloroform until it all evaporated. The experiment was a grand success, and Simpson and his colleagues lost no time in having large supplies of chloroform manufactured to use on their patients. Its use spread rapidly, as it was easy to obtain and administer and less harsh in its effects than ether. Simpson wrote extensively in defense of the substance, countering doctors and clergymen who argued that pain was necessary for the body and ordained by the Bible.

Both inventions seemed to prove 19th-century ideas about boundless technological progress and the perfectibility of humankind. Nevertheless, objections to anesthesia—especially when used for women in labor—continued. John D. Michenfelder Michenfelder, John D. Sessler Anesthesiology Editor-in-Chief Dr. Philip Larson has participated in the interview of Dr. William K. Hamilton: Hamilton, William K. James C.

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Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. The operation was judged a success and surgeons across Europe and America were quick to see the potential benefits of a general anaesthesia.

In Edinburgh, Professor of Midwifery James Young Simpson became an enthusiastic advocate of anaesthesia and pioneered its use for women during childbirth. Simpson discovered an alternative anaesthetic to ether—chloroform, a sweet-smelling, dense liquid. Chloroform received the royal seal of approval when Dr John Snow administered it to Queen Victoria during the birth of two of her children. Surgeons in England shifted to chloroform because it was easier to use, while the Americans stuck to ether because it had fewer risks.

But w hether it was ether or chloroform, by the end of the 19th century general anaesthetics were widely accepted. Early anaesthetic equipment followed the inhalation method of putting some drops of ether or chloroform on a cloth and placing it over the patient's nose and mouth. Later equipment was designed for gases and the method of administration switched to injections with pharmaceutical anaesthetics. Local anaesthetics and pain relief could also be applied as eye drops, creams and tablets.

In the early days of general anaesthesia, surgeons such as Joseph Lister continued to use the 'soporific sponge' method of inhaling anaesthetic by put a cloth with a few drops of ether or chloroform over the patient's mouth and nose. Early inhaler for ether anaesthesia, — But several people had already used ether as an anaesthetic.

John Snow was probably Britain's first anaesthesia specialist. He promoted its use and wrote to the press to correct misconceptions about the effects of chloroform. John Snow —58 was the first specialist anaesthetist in Britain. He originally described his inhaler in Clearly intended for his upper class patients, such as Queen Victoria, the brass face mask is lined with velvet. Joseph Thomas Clover — demonstrating his anaesthetic equipment on a patient.

Clover was one of the earliest doctors to specialise in anaesthesia. John H Morgan — , a surgeon, introduced his ether inhaler in the s. His design aimed to better control the dosage, and to reduce the amount of ether vapour escaping into the room and making the anaesthetist and surgeon drowsy. An anesthetist doing intubation inserting a catheter into the airway guided by a laryngoscope, Patients needed intubation if muscle relaxants were used for surgery and they needed a ventilator to help them breathe.

The basis of the modern anaesthetic machine was pioneered by Henry Gaskin Boyle — , an anaesthetist. The original machine from was carried around in a wooden box and used ether and nitrous oxide. This one has vaporisers for ether and trilene, flowmeters for oxygen, cyclopropane and nitrous oxide and rebreathing bag, — The chloroform ampoules are made of glass with a wrapping of gauze and cotton wool.

They were used during childbirth by crushing an ampoule and allowing the woman to inhale chloroform vapour from the gauze. A mixture of morphine for pain relief and a memory suppressant called scopolaminem were given to the women during labour. The sedation usually resulted in a lack of inhibitions and women were often physically restrained during labour. Many complained that the memory loss also denied them the experience of childbirth.

Pencil drawing showing a pregnant woman recieving an epidural injection into her spine to relieve the pain of labour.

By Heather Spears. This is a common form of pain relief used during childbirth. Developed in the s. Advances in chemistry and pharmacology led to the manufacture of effective pharmaceutical anaesthetics. At first these were extracted from the plants used in traditional sedatives, but later new drugs were synthesised, which were more effective and had fewer side-effects. Pharmaceutical drugs were administered intravenously, by injection, which meant that they were even faster to take effect than inhaled vapours and gases.

They also had some very dark uses. Samuel Guthrie, who combined whiskey with chlorinated lime in an attempt to produce a cheap pesticide. In , the Scottish physician Sir James Young Simpson first used the sweet-smelling, colorless, non-flammable liquid as an anesthetic. When administered by dripping the liquid onto a sponge or cloth held so that the patient inhaled the vapors, chloroform was seen to have narcotic effects on the central nervous system, and produced these effects relatively quickly.

On the other hand, there were higher risks associated with chloroform than with ether, and its administration required greater physician skill. There were early reports of fatalities due to chloroform, beginning with a year-old girl in Skill and care were required to differentiate between an effective dose enough to make patient insensible during surgery and one that paralyzed the lungs, causing death.

Fatalities were widely publicized, and the risks involved led some patients facing surgery to decline anesthesia and brave the pain. American military doctors began using ether as an anesthetic on the battlefield during the Mexican-American War , and by it was officially issued by the U.

Though many army doctors and nurses had experience with using ether by the time of the Civil War , chloroform became more popular during that conflict, due to its faster-acting nature and a large number of positive reports of its usage during the Crimean War in the s. During the Civil War, chloroform was used whenever it was available to reduce the pain and trauma of amputation or other procedures.

Usage of ether and chloroform later declined after the development of safer, more effective inhalation anesthetics, and they are no longer used in surgery today. Chloroform in particular came under attack in the 20th century, and was shown to be carcinogenic by ingestion in laboratory mice and rats.

It is now used mainly in the preparation of fluorocarbons, used in aerosol propellants and refrigerants; it is also found in some cough and cold medicines, dental products including toothpaste and mouthwashes , topical liniments and other products. But if you see something that doesn't look right, click here to contact us!



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