The leaves contain plant compounds called flavonoids and polyphenols, which have antioxidant, anti-inflammatory, and antibacterial properties. Researchers have only recently begun to examine how plant compounds influence health and disease. As a result, few scientific studies have investigated the use of neem oil in general skincare or as a treatment for skin conditions. Authors of a review of the available research into medicinal uses of neem concluded that its extracts can help treat a variety of skin conditions, including:.
First, however, it is important to note that most of the studies involved cell lines or animals. Those that did involve humans only included small numbers of participants. This makes it difficult to draw conclusions about the effectiveness of neem in the general population. A study investigated the anti-aging effects of topical neem leaf extract in hairless mice.
The researchers first exposed the mice to skin-damaging ultraviolet B radiation. They then applied neem oil to the skin of some of the rodents. The researchers also found that the extract boosted levels of a collagen-producing enzyme called procollagen and a protein called elastin.
Production of these compounds decreases as people age. This eventually leads to dry, deflated-looking, thin skin and the formation of wrinkles. In one animal study , researchers discovered that neem oil showed superior wound healing effects, compared with Vaseline. Specifically, the rats that received topical neem oil healed more quickly. They also developed stronger and more resilient tissue at the sites of their wounds. A similar study compared the effects of saline and neem oil on wound healing in rats.
Those that received neem oil healed faster and did not develop raised scars. The researchers speculated that compounds in neem oil may promote blood vessel and connective tissue growth, thus enhancing wound healing.
A study investigated whether a gel containing neem oil and St. The study involved 28 human participants who were receiving radiation therapy for head and neck cancer. All participants experienced some reduction in skin toxicity following treatment with the gel. However, it is important to note that this study did not include a placebo control. A study examined the antibacterial properties of cosmetic products containing neem compounds.
The authors found that soaps containing extracts of neem leaf or neem bark prevented the growth of several strains of bacteria. Most people can use neem oil safely. It can, for example, cause allergic reactions, such as contact dermatitis. Also, while ingesting trace amounts of neem oil will likely not cause harm, consuming large quantities can cause adverse effects, especially in children. These may include:. People should use organic, cold-pressed neem oil.
The oil should have a cloudy, yellow-brown color and a strong odor. The advantage of this approach is that it offers the potential to control agricultural pests, without serious impacts on the environment, non-target organisms, and animal and human health. Botanical insecticides must meet the same criteria as conventional insecticides. In other words, they must be selective for the target pest and provide sufficient residual activity to protect the plant during the period of vulnerability.
Over the past decade, there has been a significant increase in the number of publications concerning the use of neem oil to control agricultural pests Montes-Molina et al. However, many studies have only involved testing at the laboratory level in vitro , due to the instability of this substance under field conditions.
From these studies, it is not possible to draw firm conclusions concerning the in vivo biological efficacy of the formulations, due to the effects of numerous environmental variables. In order to overcome the above-mentioned limitations, nanotechnology has emerged as a novel tool to address the problems of agricultural sustainability and food security Khot et al.
Many studies have shown that the encapsulation of agrochemicals in nanoparticulate systems can enhance the efficacy of the active ingredient, decrease toxicity toward the environment and humans, and reduce losses due to volatilization, leaching, and photobleaching Kulkarni et al.
From the point of view of sustainable agriculture, nanotechnology can help in the development of environmentally friendly agricultural inputs, improving the safety and stability of active agents, enhancing their activity in pest control, and, consequently, increasing their acceptance by producers Nair et al. The use of nanoparticles provides an effective means of protecting neem oil against premature degradation, resulting in prolongation of its effect on the target pest.
Sustained release of the active agent is achieved, and environmental damage is minimal because the polymers employed are biodegradable. Furthermore, the number of applications of neem oil can be reduced, bringing substantial economic benefits Kulkarni et al. Although studies have demonstrated the beneficial effects of nanoencapsulation of neem oil, some issues need to be resolved so that the synergistic effect of nanoparticles associated with this botanical insecticide can significantly contribute to the control of insect pests.
Given the importance of neem oil and its worldwide use for combating numerous pests in different crops, the nanoencapsulation of this oil should enable the production of more stable formulations for the control of insects that damage crops, especially those that are essential for human consumption.
In addition, the use of nanotechnology is an excellent way to combat the development of resistance in insects due to the indiscriminate use of neem oil. LF and RdL contributed to the discussion and revised the manuscript. All authors approved the final manuscript. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Abdel-Shafy, S. In vitro acaricidal effect of plant extract of neem seed oil Azadirachta indica on egg, immature, and adult stages of Hyalomma anatolicum excavatum Ixodoidea: Ixodidae. Agrawal, S. Nanotechnology pros and cons to agriculture: a review. Google Scholar. Ahmad, S. Crop Prot. Bakry, A.
Microencapsulation of oils: a comprehensive review of benefits, techniques, and applications: encapsulation of marine, vegetable, essential oils. Food Sci. Food Saf. Boeke, S. Safety evaluation of neem Azadirachta indica derived pesticides. Brahmachari, G. Neem—an omnipotent plant: a retrospection. Chembiochem 5, — Chandramohan, B. Neem by-products in the fight against mosquito-borne diseases: biotoxicity of neem cake fractions towards the rural malaria vector Anopheles culicifacies Diptera: Culicidae.
Asian Pac. Cox, C. Reform 22, 14— Effects of different formulations of neem oil-based products on control Zabrotes subfasciatus Boheman, Coleoptera: Bruchidae on beans. Stored Prod. De Jong, W. Drug delivery and nanoparticles: applications and hazards. Application of nanotechnology for the encapsulation of botanical insecticides for sustainable agriculture: prospects and promises. Devi, N. Doutt, R. Dubey, N.
Prospects of botanical pesticides in sustainable agriculture. Ehler, L. Pest Manag. EPA Esmaeili, A. In vitro release and biological activities of Carum copticum essential oil CEO loaded chitosan nanoparticles.
Feng, R. Selection for resistance to azadirachtin in the green peach aphid, Myzus persicae. Experientia 51, — Forim, M.
Formentini, M. Insecticidal activity of neem oil against Gyropsylla spegazziniana Hemiptera: Psyllidae nymphs on Paraguay tea seedlings. Fraceto, L. Nanotechnology in agriculture: which innovation potential does it have? Gahukar, R. Factors affecting content and bioefficacy of neem Azadirachta indica A. Ghosh, A. Plant extracts as potential mosquito larvicides. Indian J. Giongo, A. Evaluation of neem-based nanoformulations as alternative to control fall armyworm.
Girish, K. Neem—a green treasure. Gonzalez-Coloma, A. Reedijk Amsterdam: Elsevier. Hasan, F. Toxic effects of neem-based insecticides on Pieris brassicae Linn.
Islam, M. The integrated use of entomopathogenic fungus, Beauveria bassiana with botanical insecticide, neem against Bemisia tabaci on eggplant. Res 5, — Combined effect of Beauveria bassiana with neem on virulence of insect in case of two application approaches.
Plant Sci. Isman, M. Botanical insecticide research: many publications, limited useful data. Trends Plant Sci. Insecticidal activity of essential oils to the tobacco cutworm, Spodoptera litura. Fitoterapia 72, 65— Joint Research Centre EU Science Hub. Kah, M. Nanopesticides and nanofertilizers: emerging contaminants or opportunities for risk mitigation? Nanopesticide research: current trends and future priorities.
Kashyap, P. Chitosan nanoparticle based delivery systems for sustainable agriculture. Khot, L. Applications of nanomaterials in agricultural production and crop protection: a review. Kogan, M. Integrated pest management: historical perspectives and contemporary developments. Kookana, R. Nanopesticides: guiding principles for regulatory evaluation of environmental risks.
Food Chem. Kulkarni, A. Urea—formaldehyde crosslinked starch and guar gum matrices for encapsulation of natural liquid pesticide [ Azadirachta Indica A. Landis, D. Habitat management to conserve natural enemies of arthropod pests in agriculture.
Li, S. Lethal and sublethal effects of a neem-based insecticide on balsam fir sawfly Hymenoptera: Diprionidae. Lokanadhan, S. Neem products and their agricultural applications. Lucantoni, L. Effects of a neem extract on blood feeding, oviposition and oocyte ultrastructure in Anopheles stephensi Liston Diptera: Culicidae. A dry, scaly scalp might be scalp eczema. Learn what symptoms to look for, causes, how to treat the condition, and how to prevent flare-ups.
Topical steroid creams are one of the most commonly used eczema treatments. We explain what they are, how to use them, possible side effects, and more. PUVA is a treatment for severe atopic dermatitis that hasn't responded well to other options. PUVA combines phototherapy and medications called….
Health Conditions Discover Plan Connect. Research How to use it Side effects Bottom line What is neem oil? Some of those ingredients include: fatty acids EFA limonoids vitamin E triglycerides antioxidants calcium It has been used in beauty regimens and skin care to: treat dry skin and wrinkles stimulate collagen production reduce scars heal wounds treat acne minimize warts and moles Neem oil may also be used to treat the symptoms of psoriasis , eczema , and other disorders of the skin.
Is there any science that supports using neem oil for skin care? How to use neem oil on your skin. What to know before you put neem oil on your skin. The bottom line. Read this next. The 12 Best Foods for Healthy Skin. Medically reviewed by Sara Perkins, MD. All About Scalp Eczema A dry, scaly scalp might be scalp eczema. Steroid Cream for Eczema: Options and What to Know Topical steroid creams are one of the most commonly used eczema treatments.
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